Gonadoblastoma historical perspective
Gonadoblastoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Historical Perspective
Discovery
- Gonadoblastoma was first discovered by Dr. Scully, an American pathologist, in 1953 following studying the pathology of a series of tumors suspected of being dysgerminomas. .[1]
- The association between GBY gene (GonadoBlastoma on Y chromosome) and gonadoblastoma was made in 1986.[2]
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of
References
- ↑ Scully, Robert E. (1953). "Gonadoblastoma. A gonadal tumor related to the dysgerminoma (Seminoma) and capable of sex-hormone production". Cancer. 6 (3): 455–463. doi:10.1002/1097-0142(195305)6:3<455::AID-CNCR2820060303>3.0.CO;2-U. ISSN 0008-543X.
- ↑ Page DC (1987). "Hypothesis: a Y-chromosomal gene causes gonadoblastoma in dysgenetic gonads". Development. 101 Suppl: 151–5. PMID 3503713.