Cancer of unknown primary origin medical therapy
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Cancer of unknown primary origin Microchapters |
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Differentiating Cancer of Unknown Primary Origin from other Diseases |
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Diagnosis |
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Treatment |
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Cancer of unknown primary origin medical therapy On the Web |
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Risk calculators and risk factors for Cancer of unknown primary origin medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There is no treatment for cancer of unknown primary origin; the mainstay of therapy is supportive care.
Medical Therapy
Medical Therapy
- There is no treatment for cancer of unknown primary origin; the mainstay of therapy is supportive care.[1]
- The treatment for cancer of unknown primary origin will depend on several factors, such as metastatic origin, biopsy findings, patients age, and performance status.
- Medical therapy for cancer of unknown primary origin should be adjusted on an individual basis and according to well-defined clinicopathologic subsets.[1]
- The table below summarizes different types of medical therapy strategies for cancer of unknown primary origin.
| Treatment for cancer of unknown primary origin Adapted from the European Society of Medical Oncology[1] | |
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| Sub-type | Proposed treatment |
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Poorly differentiated carcinoma, predominately nodal disease |
Platinum based combination chemotherapy |
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Peritoneal carcinomatosis in female |
Platinum based chemotherapy |
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Isolated axillary nodal metastases in female |
Identical to breast cancer with similar nodal involvement |
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Irradiation for N1-N2 disease. | |
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Liver, bone, or multiple-site metastases of adenocarcinoma |
Low toxicity chemotherapy of palliative orientation or best supportive care are acceptable |