Ovarian germ cell tumor laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal for patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name]. The laboratory findings associated with ovarian germ cell tumor are serum lactate dehydrogenase (LDH), human chorionic gonadotropin (HCG), CA-125, and alpha-fetoprotein (AFP).[1]
Ovarian germ cell tumor Laboratory Findings
The tumor marker associated with ovarian germ cell tumor subtypes are as follows:[1]
| Ovarian germ cell tumor subtype | Tumor markers expressed |
| Dysgerminoma |
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| Endodermal sinus tumor or yolk sac tumors |
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| Embryonal Carcinoma |
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| Teratoma |
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| Choriocarcinoma |
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- Mature teratoma is associated with increased level of CA 19-9. [2]
- There is a report suggesting a role for increased levels of CA 125, CA 153, and AFP tumor markers in differentiating the immature teratoma and mature teratoma.[3]
There are no diagnostic laboratory findings associated with [disease name].
OR
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
[Test] is usually normal among patients with [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include:
- [Abnormal test 1]
- [Abnormal test 2]
- [Abnormal test 3]
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
References
- ↑ 1.0 1.1 Ovary: Germ cell tumors. http://atlasgeneticsoncology.org/Tumors/OvarianGermCellID5067.html. URL Accessed on November 10, 2015
- ↑ Yayla Abide, Çiğdem; Bostancı Ergen, Evrim (2018). "Retrospective analysis of mature cystic teratomas in a single center and review of the literature". Journal of Turkish Society of Obstetric and Gynecology. 15 (2): 95–98. doi:10.4274/tjod.86244. ISSN 1307-699X.
- ↑ Chen C, Li JD, Huang H, Feng YL, Wang LH, Chen L (January 2008). "[Diagnostic value of multiple tumor marker detection for mature and immature teratoma of the ovary]". Ai Zheng (in Chinese). 27 (1): 92–5. PMID 18184473.