Carotid body tumor diagnostic study of choice
|
Carotid body tumor Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Carotid body tumor diagnostic study of choice On the Web |
|
American Roentgen Ray Society Images of Carotid body tumor diagnostic study of choice |
|
Risk calculators and risk factors for Carotid body tumor diagnostic study of choice |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Diagnostic Study of Choice
- The carotid body tumor is diagnosed primarily by history and physical examination.[1]
- Imaging studies are necessary to make the final diagnosis.
- Traditionally, digital subtraction angiography (DSA) has been the golden standard for the diagnosis of carotid body tumor.
- However, DSA has been replaced by other imaging studies such as CT angiography and MR angiography which provides an accurate angiogram as well as information on the local extension of the tumor to the adjacent tissues.[2]
- Color Doppler ultrasound has been recommended as a method of screening for the diagnosis of carotid body tumor.[3]
- This method is useful in the diagnosis of Shamblin’s type and intralesional blood flow of the tumor before the metastasis.[2]
- CT imaging is useful in the diagnosis of local invasion of the tumor to adjacent arteries and skull base.
- CT imaging combined with color doppler ultrasound has been suggested as the optimal detection modality for the assessment and management of the tumor.
- Since the tumor is highly vascular, incisional biopsy and percutaneous needle aspiration are contraindicated and it may cause complications such as:[4]
- Massive bleeding
- Pseudoaneurysm formation
- Carotid thrombosis
The comparison of various diagnostic studies for carotid body tumor
| Test | Sensitivity | Specificity | Accuracy |
|---|---|---|---|
| CT angiography | 100% | ...% | 100% |
| Color Doppler ultrasound | 89.8% | 82.6% | 87.5% |
Study of choice
- Genetic analysis should be considered for patients with:[5]
- A positive family history
- Presence of multiple paragangliomas
- Those who manifest the tumor before 50 years of age
Diagnostic results
The following finding(s) on performing [investigation name] is(are) confirmatory for [disease name]:
- [Finding 1]
- [Finding 2]
Sequence of Diagnostic Studies
The [name of investigation] must be performed when:
- The patient presented with symptoms/signs 1, 2, and 3 as the first step of diagnosis.
- A positive [test] is detected in the patient, to confirm the diagnosis.
OR
The various investigations must be performed in the following order:
- [Initial investigation]
- [2nd investigation]
Name of Diagnostic Criteria
- There are no established criteria for the diagnosis of carotid body tumor.
- There is no accepted histologic criteria for the diagnosis of malignancy in the carotid body tumor. To confirm malignant transformation of the tumor,
References
- ↑ Luo T, Zhang C, Ning YC, Gu YQ, Li JX, Wang ZG (March 2013). "Surgical treatment of carotid body tumor: case report and literature review". J Geriatr Cardiol. 10 (1): 116–8. doi:10.3969/j.issn.1671-5411.2013.01.018. PMC 3627704. PMID 23610583.
- ↑ 2.0 2.1 Jin, Zhan-Qiang; He, Wen; Wu, Dong-Fang; Lin, Mei-Ying; Jiang, Hua-Tang (2016). "Color Doppler Ultrasound in Diagnosis and Assessment of Carotid Body Tumors: Comparison with Computed Tomography Angiography". Ultrasound in Medicine & Biology. 42 (9): 2106–2113. doi:10.1016/j.ultrasmedbio.2016.04.007. ISSN 0301-5629.
- ↑ Worsey, M.J.; Laborde, A.L.; Bower, T.; Miller, E.; Kresowik, T.F.; Sharp, W.J.; Corson, J.D. (1992). "An Evaluation of Color Duplex Scanning in the Primary Diagnosis and Management of Carotid Body Tumors". Annals of Vascular Surgery. 6 (1): 90–94. doi:10.1007/BF02000675. ISSN 0890-5096.
- ↑ Mirov, Andrew G. (1962). "Benign and Malignant Carotid Body Tumors". JAMA: The Journal of the American Medical Association. 181 (1): 13. doi:10.1001/jama.1962.03050270015003. ISSN 0098-7484.
- ↑ Davila, Victor J.; Chang, James M.; Stone, William M.; Fowl, Richard J.; Bower, Thomas C.; Hinni, Michael L.; Money, Samuel R. (2016). "Current surgical management of carotid body tumors". Journal of Vascular Surgery. 64 (6): 1703–1710. doi:10.1016/j.jvs.2016.05.076. ISSN 0741-5214.