Friedreich's ataxia electrocardiogram
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: MMJ
Overview
Electrocardiogram
An ECG may be helpful in the diagnosis of Friedreich's ataxia. Findings on an ECG suggestive of Friedreich's ataxia include:[1][2][3][4][5]
- T-wave repolarization abnormalities, especially in the inferior and lateral leads, is the most common abnormalities seen on the electrocardiogram (ECG) of patients with Friedreich's ataxia(approximately 85%).
- Bundle branch blocks is found in 15% of patients with Friedreich's ataxia
- The QT interval and the QRS wave is usually normal, indicating that there is a relatively low risk for ventricular tachyarrhythmias
References
- ↑ Hanson E, Sheldon M, Pacheco B, Alkubeysi M, Raizada V (January 2019). "Heart disease in Friedreich's ataxia". World J Cardiol. 11 (1): 1–12. doi:10.4330/wjc.v11.i1.1. PMC 6354072. PMID 30705738.
- ↑ Payne RM, Wagner GR (September 2012). "Cardiomyopathy in Friedreich ataxia: clinical findings and research". J. Child Neurol. 27 (9): 1179–86. doi:10.1177/0883073812448535. PMC 3674565. PMID 22764179.
- ↑ Pousset F, Legrand L, Monin ML, Ewenczyk C, Charles P, Komajda M, Brice A, Pandolfo M, Isnard R, Tezenas du Montcel S, Durr A (November 2015). "A 22-Year Follow-up Study of Long-term Cardiac Outcome and Predictors of Survival in Friedreich Ataxia". JAMA Neurol. 72 (11): 1334–41. doi:10.1001/jamaneurol.2015.1855. PMID 26414159.
- ↑ Payne RM, Peverill RE (December 2012). "Cardiomyopathy of Friedreich's ataxia (FRDA)". Ir J Med Sci. 181 (4): 569–70. doi:10.1007/s11845-012-0808-7. PMID 22373590.
- ↑ Weidemann F, Störk S, Liu D, Hu K, Herrmann S, Ertl G, Niemann M (August 2013). "Cardiomyopathy of Friedreich ataxia". J. Neurochem. 126 Suppl 1: 88–93. doi:10.1111/jnc.12217. PMID 23859344.