Renal oncocytoma other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]
Overview
There are no other diagnostic study findings associated with renal oncocytoma.
Other Diagnostic Studies
There are no other diagnostic study findings associated with renal oncocytoma.
Overview
There are no other diagnostic studies associated with [disease name].
OR
[Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
OR
Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].
Other Diagnostic Studies
There are no other diagnostic studies associated with [disease name].
OR
[Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include:
- [Finding 1]
- [Finding 2]
- [Finding 3]
OR
Other diagnostic studies for [disease name] include:
- [Diagnostic study 1], which demonstrates:
- [Finding 1]
- [Finding 2]
- [Finding 3]
- [Diagnostic study 2], which demonstrates:
- [Finding 1]
- [Finding 2]
- [Finding 3]
Equivocal results from multiple studies investigating the use of percutaneous renal biopsy have resulted in its limited role in the diagnosis of solid renal masses. A recent small retrospective series from MD Anderson Cancer Center examined fine needle aspiration cytology of eosinophilic renal neoplasms with special stains (eg, cytokeratin, vimentin, and Hale’s colloidal iron) and electron microscopy (in selected cases), demonstrating some success in predicting final pathology [18]. However, the value of this study was limited because of its retrospective nature and the lack of surgical specimens to provide “gold standard” data from a significant number of patients felt to have oncocytoma. Frozen-section needle biopsy performed at time of renal exploration failed to yield reliable diagnoses in a recent prospective study from our institution [41]. One hundred three patients underwent radical or partial nephrectomy for their renal tumors. After resection, a “back table” biopsy was obtained from each tumor using an 18-gauge biopsy gun and sent for frozen section. Two urologic pathologists independently reviewed the specimens, and the results were compared with those from whole-mount permanent sections. Overall accuracy of the two pathologists was 76% and 80%, respectively, with nondiagnostic rates of 11% and 17%. Both pathologists diagnosed 5% of the malignant lesions as benign, and 21% and 36% of benign lesions as malignant. The quality of the biopsies themselves was clearly ideal and not subject to the vagaries inherent in percutaneous biopsies. Needle biopsy of the tumor can be a useful strategy to diagnose oncocytoma in the very elderly or very sick patient with a renal tumor. There have been cases reported in which patients with large bilateral and unresectable renal oncocytomas have been observed for many years without showing distinct tumoral progression. Such observational treatment may be entirely appropriate for patients at poor operative risk because of extensive comorbidities