Familial Mediterranean fever diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Diagnostic Study of Choice
Study of choice
Familial Mediterranean fever is primarily diagnosed based on the clinical presentation.
The comparison of various diagnostic studies for familial Mediterranean fever
| Test | Sensitivity | Specificity |
|---|---|---|
| Tel Hashomer criteria | ...% | ...% |
| Livneh criteria | ...% | ...% |
[Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity
The Tel Hashomer for diagnosing familial Mediterranean fever
| Type | Criteria |
|---|---|
| Major | I. Recurrent episodes of fever plus serositis
II. AA type of amyloidosis without predisposing disease III. Response to colchicine |
| Minor | I. Recurrent febrile attacks
II. Erysipelas-like erythema III. Family history in first-degree relatives |
The Livneh criteria for diagnosing familial Mediterranean fever[1]
| Type | Criteria |
|---|---|
| Major | Typical attacks (1-4)
1- Generalised peritonitis 2- Unilateral pleuritis or pericarditis 3- Monoarthritis (hip, knee, ankle) 4- Fever alone 5- Incomplete abdominal attack |
| Minor | Incomplete attacks involving either or both
of the following sites 1- Chest 2- Joint 3- Exertional leg pain 4- Favorable response to colchicine |
Tel Hashomer criteria
[Disease name] may be diagnosed at any time if one or more of the following criteria are met:
- Criteria 1
- Criteria 2
- Criteria 3
The diagnosis of Familial Mediterranean fever is made when at least 2 of the following diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
References
- ↑ Livneh A, Langevitz P, Zemer D, Zaks N, Kees S, Lidar T, Migdal A, Padeh S, Pras M (October 1997). "Criteria for the diagnosis of familial Mediterranean fever". Arthritis Rheum. 40 (10): 1879–85. doi:10.1002/1529-0131(199710)40:10<1879::AID-ART23>3.0.CO;2-M. PMID 9336425.