Osteosarcoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].

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Overview

CT scan in osteosarcoma may be helpful in biopsy and staging. CT scan adds little to plain radiography and MRI in direct assessment of the tumor.

CT

A CT scan of the primary osteosarcoma lesion helps delineate the location and extent of the tumor and is critical for surgical planning[1][2][3][4][5]:

  • CT scan in osteosarcoma may be helpful in biopsy and staging.
  • CT scan adds little to plain radiography and MRI in direct assessment of the tumor.
  • The exception to this rule is predominantly lytic lesions in which small amounts of mineralised material may be inapparent on both plain film and MRI.
  • CT scan is used to:
  • Observe the extent of the bone tumor.
  • Observe if the tumor has spread into nearby tissues.
  • Guide a biopsy needle to the tumor (CT-guided biopsy).
  • Observe if the bone cancer has spread to the lung (metastasis).

References

  1. Isakoff MS, Bielack SS, Meltzer P, Gorlick R (September 2015). "Osteosarcoma: Current Treatment and a Collaborative Pathway to Success". J. Clin. Oncol. 33 (27): 3029–35. doi:10.1200/JCO.2014.59.4895. PMC 4979196. PMID 26304877.
  2. Sue M, Oda T, Sasaki Y, Kameta A, Okada Y, Ogura I (2017). "Osteosarcoma of the Mandible: a Case Report with CT, MRI and Scintigraphy". Chin J Dent Res. 20 (3): 169–172. doi:10.3290/j.cjdr.a38772. PMID 28808701.
  3. Heaton TE, Hammond WJ, Farber BA, Pallos V, Meyers PA, Chou AJ, Price AP, LaQuaglia MP (January 2017). "A 20-year retrospective analysis of CT-based pre-operative identification of pulmonary metastases in patients with osteosarcoma: A single-center review". J. Pediatr. Surg. 52 (1): 115–119. doi:10.1016/j.jpedsurg.2016.10.034. PMC 5384104. PMID 27836366.
  4. Huang L, Xia W, Zhang B, Qiu B, Gao X (May 2017). "MSFCN-multiple supervised fully convolutional networks for the osteosarcoma segmentation of CT images". Comput Methods Programs Biomed. 143: 67–74. doi:10.1016/j.cmpb.2017.02.013. PMID 28391820.
  5. Xia T, Guan Y, Chen Y, Li J (July 2014). "Askin tumor: CT and FDG-PET/CT imaging findings and follow-up". Medicine (Baltimore). 93 (6): e42. doi:10.1097/MD.0000000000000042. PMC 4602428. PMID 25058144.

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