Retinoblastoma MRI
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Retinoblastoma MRI On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Simrat Sarai, M.D. [3]
Overview
MRI findings of retinoblastoma include hyperintense mass on T1-weighted MRI and hypointense mass on T2-weighted MRI.
MRI
- MRI imaging study of retinoblastoma was first introduced in1980.[1]
- MRI is accurate for tumor staging and evaluation of metastatic risk factors.[2]
- It is also used as an additional diagnostic tool in suspected retinoblastoma cases.[3]
- MRI's diagnostic value in the diagnosis of advanced retinoblastoma is greater than CT scan.[4]
- MRI findings diagnostic of retinoblastoma are:
- On T1 image: Hyperintense mass compared to vitreous body
- On T2 image: Hypointense mass compared to vitreous body
- MRI can differentiate the tumor with secondary retinal detachment from other causes of subretinal effusion or detachment, such as Coats' disease, primary hyperplastic vitreous, and retinopathy of prematurity.
- Also, some experts argue that CT imaging studies in bilateral retinoblastoma will increase the risk of future malignancies. MRI is not associated with such risk.
- MRI is also the study of choice to rule out extra-ocular extension of the tumor.[3]
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References
- ↑ Schueler, A O (2003). "High resolution magnetic resonance imaging of retinoblastoma". British Journal of Ophthalmology. 87 (3): 330–335. doi:10.1136/bjo.87.3.330. ISSN 0007-1161.
- ↑ de Graaf, Pim; Barkhof, Frederik; Moll, Annette C.; Imhof, Saskia M.; Knol, Dirk L.; van der Valk, Paul; Castelijns, Jonas A. (2005). "Retinoblastoma: MR Imaging Parameters in Detection of Tumor Extent". Radiology. 235 (1): 197–207. doi:10.1148/radiol.2351031301. ISSN 0033-8419.
- ↑ 3.0 3.1 Meel R, Radhakrishnan V, Bakhshi S (April 2012). "Current therapy and recent advances in the management of retinoblastoma". Indian J Med Paediatr Oncol. 33 (2): 80–8. doi:10.4103/0971-5851.99731. PMC 3439795. PMID 22988349.
- ↑ de Jong, Marcus C.; de Graaf, Pim; Noij, Daniel P.; Göricke, Sophia; Maeder, Philippe; Galluzzi, Paolo; Brisse, Hervé J.; Moll, Annette C.; Castelijns, Jonas A. (2014). "Diagnostic Performance of Magnetic Resonance Imaging and Computed Tomography for Advanced Retinoblastoma". Ophthalmology. 121 (5): 1109–1118. doi:10.1016/j.ophtha.2013.11.021. ISSN 0161-6420.