Progeria epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is very rare. The usual age of diagnosis for Hutchinson-Gilford progeria syndrome (HGPS) ia around two to three years of age.

Epidemiology and Demographics

Incidence

• The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.
• The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.

Prevalence

• The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.

Age

• Hutchinson-Gilford progeria syndrome (HGPS) commonly affects individuals of very younger age rather than older age.
• The median age at diagnosis is 2.9 years overall.

Race

• There is no race predilection of Hutchinson-Gilford progeria syndrome (HGPS) till now.

Gender

• Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome (HGPS) than females.
• The male to female ratio is approximately 1.2:1.

Region

• The majority of [disease name] cases are reported in [geographical region].

• [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].