Hepatopulmonary syndrome classification

Hepatopulmonary syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

There is no established system for the classification of hepatopulmonary syndrome.

Classification

There is no established system for the classification of hepatopulmonary syndrome (HPS).

HPS can be classified in term of severity based on atrial blood gas analysis, as follows:

• Mild: Alveolar-arterial oxygen gradient above, or equal to<math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 80mmHg.
• Moderate: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen <math>\geq</math> 60 up to 80mmHg.
• Severe: Alveolar-arterial oxygen gradient <math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 50 up to 60mmHg.
• Very severe: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen below 50 mmHg (< 300mmHg while the patient is breathing 100% oxygen).