Follicular thyroid cancer medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Pharmacologic medical therapies for follicular thyroid cancer include radioactive iodine therapy and targeted medical therapy.
Medical Therapy
Thyroid Hormone Replacement
- Thyroxine is recommended as a replacement therapy for all patients with follicular thyroid cancer especially for micronodular pulmonary metastases.[1]
Radioactive Iodine Therapy
- Radio active iodine ablation therapy may be used to prevent the recurrence of cancer.
- High doses of radioiodine is also used to treat microscopic bone metastasis
Targeted Therapy
Kinase Inhibitors
- Sorafenib
- Lenvatinib
Radiation Therapy
- External radiation therapy is used for bone pain in bone metastasis.
Other Treatment Options
- Intravenous infusions of bisphosphonate is also used to reduce pain in bone metastasis.
- Corticosteroid therapy is recommended for cerebral edema secondary to brain metastasis.
Treatment Options for Follicular Thyroid Cancer
| Follicular thyroid cnacer treatment | |||||||||||||||||||||||||||||||||||||
| Localized or regional tumor | Metastatic | Recurrent | |||||||||||||||||||||||||||||||||||
| Surgery Total thyroidectomy Lobectomy RAI therapy Thyroid suppression therapy EBRT | Surgery ± postoperative RAI therapy Targeted therapy EBRT Chemotherapy | ||||||||||||||||||||||||||||||||||||
| Iodine sensitive | Iodine resistent | ||||||||||||||||||||||||||||||||||||
| RAI therapy Thyroid suppression therapy | Thyroid suppression therapy Targeted therapy Surgery EBRT | ||||||||||||||||||||||||||||||||||||
| Follicular Thyroid Cancer Treatment Options |
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Reference
- ↑ McHenry, C. R.; Phitayakorn, R. (2011). "Follicular Adenoma and Carcinoma of the Thyroid Gland". The Oncologist. 16 (5): 585–593. doi:10.1634/theoncologist.2010-0405. ISSN 1083-7159.