Medullary thyroid cancer classification
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Differentiating Medullary thyroid cancer from other Diseases |
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Medullary thyroid cancer classification On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Medullary thyroid cancer may be classified according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and inherited medullary thyroid cancer.
Classification
- Medullary thyroid cancer may be classified according to the mode of occurrence into 2 groups: sporadic medullary thyroid cancer and inherited medullary thyroid cancer.
- Sporadic medullary thyroid cancer[1]
- Sporadic medullary thyroid cancer (75% of the cases)
- Inherited medullary thyroid cancer (25% of the cases)
- MEN2A (23%)
- MEN2B (2%)
- Familial medullary thyroid cancer (FMTC)(rare)
- Medullary thyroid cancer may be classified according to histologic variants into:[2]
- Papillary or pseudopapillary due to the presence of papillary structures or artifactual structures resembling papillae.
- Glandular
- Giant cells
- Spindle cell
- Small cell and Neuroblastoma-like
- Paraganglioma-like
- Onchocytic cell
- Clear cell
- Angiosarcoma-like
- Squamous cell
- Melanin-producing
- Amphicrine
Reference
- ↑ Thyroid Cancer Cancer.gov (2015). http://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#link/stoc_h2_2- Accessed on October, 29 2015
- ↑ DeLellis, Ronald (2004). Pathology and genetics of tumours of endocrine organs. Lyon: IARC Press. ISBN 92-832-2416-7.