Hepatopulmonary syndrome classification
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Differentiating Hepatopulmonary syndrome from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
There is no established system for the classification of hepatopulmonary syndrome.
Classification
There is no established system for the classification of hepatopulmonary syndrome (HPS).[1]
HPS can be classified in term of severity based on atrial blood gas analysis, as follows:
- Mild: Alveolar-arterial oxygen gradient above, or equal to<math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 80mmHg.
- Moderate: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen <math>\geq</math> 60 up to 80mmHg.
- Severe: Alveolar-arterial oxygen gradient <math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 50 up to 60mmHg.
- Very severe: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen below 50 mmHg (< 300mmHg while the patient is breathing 100% oxygen).[2]
References
- ↑ Rodríguez-Roisin R, Krowka MJ (2008) Hepatopulmonary syndrome--a liver-induced lung vascular disorder. N Engl J Med 358 (22):2378-87. DOI:10.1056/NEJMra0707185 PMID: 18509123
- ↑ Krowka MJ, Fallon MB, Kawut SM, Fuhrmann V, Heimbach JK, Ramsay MA et al. (2016) International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension. Transplantation 100 (7):1440-52. DOI:10.1097/TP.0000000000001229 PMID: 27326810