Primary cutaneous follicle centre lymphoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The incidence of primary cutaneous follicle centre lymphoma increases with age; the median age at diagnosis is 51 years. Males are more commonly affected with primary cutaneous follicle centre lymphoma than females.[1]
Epidemiology and Demographics
According to a large population-based study focused on cutaneous lymphomas (CL) in the United States by Bradford et al. on 3884 Cutaneous lymphomas 9CLs) diagnosed during 2001-2005. Cutaneous T-cell lymphomas (CTCLs) accounted for 71% (age-adjusted incidence rate [IR] = 7.7/1 000 000 person-years), whereas cutaneous B-cell lymphomas(CBCLs) accounted for 29% (IR = 3.1/1 000 000 person-years).[2]
Over the past 25 years, the CL IR increased from 5.0/1 000 000 person-years during 1980-1982 to 14.3 during 2001-2003. During 2004-2005, the CL IR was 12.7. This recent apparent change could be incomplete case ascertainment or potential leveling off of IRs. CLs rates vary markedly by race and sex, supporting the notion that they represent distinct disease entities.
Incidence
- The incidence/prevalence of primary cutaneous follicle centre lymphoma is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of primary cutaneous follicle centre lymphoma was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The incidence/prevalence of primary cutaneous follicle centre lymphoma is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of primary cutaneous follicle centre lymphoma was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of primary cutaneous follicle centre lymphoma is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of primary cutaneous follicle centre lymphoma is approximately [number range].
Age
The incidence of primary cutaneous follicle centre lymphoma increases with age; the median age at diagnosis is 51 years.[1]
Race
- Primary cutaneous follicle centre lymphoma usually affects individuals of the blacks and non-Hispanic whites followed by Hispanic whites and Asian/Pacific Islanders . Whites of European descent individuals are less likely to develop primary cutaneous follicle centre lymphoma.
- According to Bradford et al. CL incidence rate were highest among blacks and non-Hispanic whites (both 11.5/1 000 000 person-years), followed by Hispanic whites (7.9) and Asian/Pacific Islanders (7.1). The CTCL IR was highest among blacks (10.0/1 000 000 person-years), whereas the CBCL IR was highest among non-Hispanic whites (3.5).[2]
Gender
Males are more commonly affected with primary cutaneous follicle centre lymphoma than females.[1]
According to Bradford et al. also, males had a statistically significant higher incidence of CL than females (14.0 vs 8.2/1 000 000 person-years, respectively; male-female IR ratio [M/F IRR] = 1.72; P < .001).[2]
Region
- The majority of primary cutaneous follicle centre lymphoma cases are reported in [geographical region].
- primary cutaneous follicle centre lymphoma is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 Primary cutaneous follicle centre lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf5ae3e27c3994bd549b/. Accessed on March 01, 2016
- ↑ 2.0 2.1 2.2 Bradford PT, Devesa SS, Anderson WF, Toro JR (2009). "Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases". Blood. 113 (21): 5064–73. doi:10.1182/blood-2008-10-184168. PMC 2686177. PMID 19279331.