Amyloidosis CT

Amyloidosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification • Primary amyloidosis • Secondary amyloidosis • Familial amyloidosis • Wild-type (senile) amyloidosis • Cardiac amyloidosis • Beta-2 microglobulin related amyloidosis • Gelsolin related amyloidosis • Lysozyme amyloid related amyloidosis • Leucocyte cell-derived chemotaxin 2 related amyloidosis • Fibrinogen A alpha-chain associated amyloidosis
Pathophysiology
Causes
Differentiating Amyloidosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Amyloidosis CT On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Amyloidosis CT All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Amyloidosis CT
CDC on Amyloidosis CT
Amyloidosis CT in the news
Blogs on Amyloidosis CT
Directions to Hospitals Treating Psoriasis
Risk calculators and risk factors for Amyloidosis CT

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[3]Sabawoon Mirwais, M.B.B.S, M.D.[4]

Overview

CT can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis.

CT

In hepatic amyloidosis the CT scan findings may include:

• Liver enlargement with heterogeneous decreased attenuation
• Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
• Parenchyma calcification (rare)

In renal amyloidosis the CT findings may include:

• Kidney enlargement with heterogeneous decreased attenuation
• Parenchyma calcification (rare)

In cardiac amyloidosis the CT findings may include:

• Heart enlargement with heterogeneous decreased attenuation
• Cardiac calcifications
• Pericardial effusion (rare)

Images

CT image showing mediastinal amyloidosis (yellow arrows). Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6711

Amyloidosis - bronchial and diffuse nodular pulmonary involvement. Case courtesy of Dr Bruno Di Muzio, Radiopaedia.org, rID: 60156