Familial amyloidosis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hereditary amyloidosis can be caused by genetic mutations in different genes including LYZ gene, fibrinogen A alpha polypeptide gene, FGA gene, APOA1 gene, lysozyme gene, and B2M gene.
Causes
Common Causes
Common causes of familial amyloidosis may include genetic mutations in:[1]
- Transthyretin (TTR)
- Apolipoprotein AI
- Apolipoprotein AII
- Fibrinogen Aa
- Lysozyme
- Gelsolin
- Cystatin C
References
- ↑ Pepys MB, Hawkins PN, Booth DR, Vigushin DM, Tennent GA, Soutar AK, Totty N, Nguyen O, Blake CC, Terry CJ (April 1993). "Human lysozyme gene mutations cause hereditary systemic amyloidosis". Nature. 362 (6420): 553–7. doi:10.1038/362553a0. PMID 8464497.