Patent foramen ovale historical perspective

Patent Foramen Ovale Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]

Overview

• In 1564, the presence of foramen ovale at birth was first described by an Italian surgeon named Leonardi Botali.