Malabsorption causes

Malabsorption
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Overview
Classification Infection Structural defect Digestive failure Systemic disease Iatrogenic
Differentiating Malabsorption from other Diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maheep Sangha, M.B.B.S. Luke Rusowicz-Orazem, B.S.

Overview

Malabsorption syndrome is commonly caused by gastroenterological conditions, including bacterial infections and other sources of liver, intestine, and pancreatic inflammation. It is also commonly caused by sources of anemia.

Causes

Life Threatening Causes

• Aids
• Atrophic gastritis
• Bacterial overgrowth
• Carcinoid syndrome
• Carcinoma of pancreas
• Chronic pancreatitis
• Cirrhosis
• Cystic fibrosis
• Hiv related malabsorption
• Ileal disease
• Intestinal lymphoma
• Intestinal trauma
• Intestinal tuberculosis
• Liver disease
• Lymphoma
• Mastocytosis
• Pancreatic insufficiencies
• Pancreatitis
• Terminal ileal disease

Common Causes

• Atrophic gastritis
• B12 malabsorption
• Celiac disease
• Celiac sprue
• Cholestasis
• Chronic pancreatitis
• Cirrhosis
• Crohn's disease
• Disaccharidase deficiency
• Gallbladder disease
• Giardia lamblia
• Giardiasis
• Hiv related malabsorption
• Intestinal radiation therapy
• Intestinal surgery
• Intestinal trauma
• Intestinal tuberculosis
• Lactase deficiency ,
• Laxative abuse,
• Liver disease,
• Menetrier disease,
• Obstructive jaundice,
• Pancreatic insufficiencies,
• Pancreatitis,
• Postgastrectomy syndrome,
• Short bowel syndrome,
• Short gut syndrome,
• Soya milk intolerance,
• Ulcerative colitis,
• Whipple's disease,

Causes by Organ System

Cardiovascular	Abetalipoproteinemia, Anderson disease, Apolipoprotein b deficiency, Cholesterol ester storage disease, Strictures, Systemic sclerosis
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Cholestatic jaundice, Collagen vascular diseases
Drug Side Effect	Colchicine, Colestyramine, Efavirenz, Laxative abuse, Metformin, Neomycin, Prolonged antibiotic use
Ear Nose Throat	No underlying causes
Endocrine	Addison's disease, Autoimmune polyendocrine syndrome type 1, Hyperparathyroidism , Hyperthyroidism, Hypoparathyroidism, Hypothyroidism
Environmental	No underlying causes
Gastroenterologic	Alagille syndrome, Atrophic gastritis , B12 malabsorption, Bile acid malabsorption syndrome, Bile salt malabsorption, Biliary atresia, Blind loops, Canada-cronkhite syndrome, Carcinoma of pancreas, Celiac disease, Celiac sprue, Cholestasis, Cholestatic jaundice, Chronic cholestasis, Chronic granulomatous disease, Chronic pancreatitis, Chylomicron retention disease, Cirrhosis, Cow's milk intolerance, Crohn's disease, Disaccharidase deficiency, Diverticulae, Eosinophilic gastroenteropathy, Fistulae, Gallbladder disease, Giardia lamblia, Giardiasis, Graft versus host disease, Hiv related malabsorption, Ileal disease , Intestinal disaccharidase deficiency, Intestinal enteropeptidase deficiency, Intestinal lymphangiectasia, Intestinal lymphoma, Intestinal radiation therapy, Intestinal surgery, Intestinal trauma, Intestinal tuberculosis, Lactase deficiency , Laxative abuse, Liver disease, Menetrier disease, Obstructive jaundice, Pancreatic insufficiencies, Pancreatitis, Pearson marrow-pancreas syndrome, Post billroth ii procedure, Postgastrectomy syndrome, Radiation enteritis, Short bowel syndrome, Short gut syndrome, Shwachman-diamond syndrome, Soya milk intolerance, Terminal ileal disease, Trichohepatoenteric syndrome 1, Tropical sprue, Ulcerative colitis, Whipple's disease, Zollinger-ellison syndrome
Genetic	Alagille syndrome, Canada-cronkhite syndrome, Disaccharidase deficiency, Hartnup's disease, Johanson-blizzard syndrome, Trypsinogen deficiency
Hematologic	3-beta-hydroxy-delta-5-c27-steroid oxidoreductase deficiency, Abetalipoproteinemia, Apolipoprotein b deficiency, B12 malabsorption, Common variable hypogammaglobulinaemia, Diabetes mellitus, Eosinophilic gastroenteropathy, Hypogammaglobulinaemia, Ileal disease , Obstructive jaundice, Pernicious anemia , Shwachman-diamond syndrome, Small bowel lymphoma, Sucrase-isomaltase deficiency, Sucrose intolerance, Terminal ileal disease
Iatrogenic	Intestinal radiation therapy, Intestinal surgery, Post billroth ii procedure, Postgastrectomy syndrome, Radiation enteritis
Infectious Disease	Aids, Bacterial overgrowth, Blind loops, Fasciolopsis buski, Fish tape worm, Giardia lamblia, Giardiasis, Hiv related malabsorption, Hookworm, Intestinal tuberculosis, Pancreatitis, Strongyloidiasis, Whipple's disease
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	Diabetes mellitus, Malnutrition
Obstetric/Gynecologic	No underlying causes
Oncologic	Carcinoid syndrome, Carcinoma of pancreas, Intestinal lymphoma, Lymphoma , Mastocytosis, Small bowel lymphoma, Zollinger-ellison syndrome
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	Gallbladder disease
Rheumatology/Immunology/Allergy	Alpha heavy chain disease, Amyloidosis, Celiac disease, Celiac sprue, Cow's milk intolerance, Crohn's disease, Cystic fibrosis, Mastocytosis, Soya milk intolerance
Sexual	Aids
Trauma	Intestinal trauma
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

• 3-beta-hydroxy-delta-5-c27-steroid oxidoreductase deficiency
• Abetalipoproteinemia
• Addison's disease
• Aids
• Alagille syndrome
• Alpha heavy chain disease
• Amyloidosis
• Anderson disease
• Apolipoprotein b deficiency
• Atrophic gastritis
• Autoimmune polyendocrine syndrome type 1
• B12 malabsorption
• Bacterial overgrowth
• Bile acid malabsorption syndrome
• Bile salt malabsorption
• Biliary atresia
• Blind loops
• Canada-cronkhite syndrome
• Carcinoid syndrome
• Carcinoma of pancreas
• Celiac disease
• Celiac sprue
• Cholestasis
• Cholestatic jaundice
• Cholesterol ester storage disease
• Chronic cholestasis
• Chronic granulomatous disease
• Chronic pancreatitis
• Chylomicron retention disease
• Cirrhosis
• Colchicine
• Colestyramine
• Collagen vascular diseases
• Common variable hypogammaglobulinaemia
• Cow's milk intolerance
• Crohn disease
• Crohn's disease
• Cystic fibrosis
• Diabetes mellitus
• Disaccharidase deficiency
• Diverticulae
• Efavirenz
• Eosinophilic gastroenteropathy
• Fasciolopsis buski
• Fish tape worm
• Fistulae
• Gallbladder disease
• Giardia lamblia
• Giardiasis
• Graft versus host disease
• Hartnup's disease
• Hiv related malabsorption
• Hookworm
• Hyperparathyroidism 
• Hyperthyroidism
• Hypogammaglobulinaemia
• Hypoparathyroidism
• Hypothyroidism 
• Ileal disease
• Intestinal disaccharidase deficiency
• Intestinal enteropeptidase deficiency
• Intestinal lymphangiectasia
• Intestinal lymphoma
• Intestinal radiation therapy
• Intestinal surgery
• Intestinal trauma
• Intestinal tuberculosis
• Johanson-blizzard syndrome
• Lactase deficiency
• Laxative abuse
• Liver disease
• Lymphoma
• Malnutrition
• Mastocytosis
• Menetrier disease
• Metformin
• Neomycin
• Obstructive jaundice
• Pancreatic insufficiencies
• Pancreatitis
• Pearson marrow-pancreas syndrome
• Pernicious anemia
• Post billroth ii procedure
• Postgastrectomy syndrome
• Prolonged antibiotic use
• Radiation enteritis
• Short bowel syndrome
• Short gut syndrome
• Shwachman-diamond syndrome
• Small bowel lymphoma
• Soya milk intolerance
• Strictures
• Strongyloidiasis
• Sucrase-isomaltase deficiency
• Sucrose intolerance
• Systemic sclerosis 
• Terminal ileal disease
• Traveller's diarrhoea
• Trichohepatoenteric syndrome 1
• Tropical sprue
• Trypsinogen deficiency
• Ulcerative colitis
• Whipple's disease
• Zollinger-ellison syndrome