Ventricular fibrillation causes

	Ventricular fibrillation Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2] Sahar Memar Montazerin, M.D.[3]

Overview

The heart pumps blood to the lungs, brain, and other organs. Interruption of the heartbeat for only a few seconds can lead to fainting (syncope) or cardiac arrest. Fibrillation is an uncontrolled twitching or quivering of muscle fibers (fibrils). When it occurs in the lower chambers of the heart, it is called ventricular fibrillation. During ventricular fibrillation, blood is not pumped from the heart. Sudden cardiac death results. The most common cause of VF is a heart attack. However, VF can occur whenever the heart muscle does not get enough oxygen.

Causes

Life Threatening Causes

Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Common causes of ventricular fibrillation include:^[2]^[3]^[4]^[5]^[6]^[7]^[8]

Cardiomyopathies
Commotio cordis
Congenital heart disease
Electrocution
Myocardial infarction
Heart surgery
Electrolyte abnormalities
- Hypokalemia
- Hypocalcemia

Causes by Organ System

Cardiovascular	Abnormal automaticity, acute myocardial rupture, aortic dissection, aortic stenosis, arrhythmogenic right ventricular dysplasia, Brugada syndrome, cardiomyopathies, commotio cordis, complete heart block, congenital heart disease, coronary artery spasm, dilated cardiomyopathy, heart attack, heart block, heart surgery, hypertrophic cardiomyopathy, hypokalemia, hypoxia, ischemic stroke, myocardial infarction, myocardial ischemia, myocarditis, pericardial tamponade, preexcitation syndrome, prolonged QT syndrome, pulmonary embolism, pulmonary hypertension, re-entry or circus motion, short QT syndrome, sudden cardiac death, sudden infant death syndrome, Sumatriptan, torsade de pointes, unstable angina, valvular heart disease, Wolff-Parkinson-White syndrome
Chemical/Poisoning	Belladonna, environmental poisoning
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Amiodarone, calcium chloride, calcium gluconate, Eletriptan, ergotamine tartrate, Fosphenytoin sodium, ibutilide, increased catecholamine levels, medications, Naratriptan, phenobarbital, pramipexole, proarrhythmic drugs
Ear Nose Throat	No underlying causes
Endocrine	Increased catecholamine levels
Environmental	Environmental poisoning
Gastroenterologic	No underlying causes
Genetic	Brugada syndrome, congenital heart disease
Hematologic	Pulmonary embolism
Iatrogenic	No underlying causes
Infectious Disease	Myocarditis, sepsis
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	Intracranial hemorrhage, ischemic stroke, Pickwickian syndrome, sleep apnea
Nutritional/Metabolic	Acid-base disturbances, electrolyte imbalance
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Aspiration, bronchospasm, hypoxia, Pickwickian syndrome, pulmonary embolism, pulmonary hypertension, sudden infant death syndrome, tension pneumothorax
Renal/Electrolyte	Electrolyte imbalance, hypokalemia
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	Electric shock, electrocution
Urologic	No underlying causes
Miscellaneous	Drowning, hyperthermia, hypothermia, idiopathic,

Causes in Alphabetical Order^[8]^[9]^[10]

References

↑ Koplan BA, Stevenson WG (March 2009). "Ventricular tachycardia and sudden cardiac death". Mayo Clin. Proc. 84 (3): 289–97. doi:10.1016/S0025-6196(11)61149-X. PMC 2664600. PMID 19252119.
↑ Khairy P (November 2016). "Ventricular arrhythmias and sudden cardiac death in adults with congenital heart disease". Heart. 102 (21): 1703–1709. doi:10.1136/heartjnl-2015-309069. PMID 27250216.
↑ Maury P, Sacher F, Rollin A, Mondoly P, Duparc A, Zeppenfeld K, Hascoet S (May 2017). "Ventricular arrhythmias and sudden death in tetralogy of Fallot". Arch Cardiovasc Dis. 110 (5): 354–362. doi:10.1016/j.acvd.2016.12.006. PMID 28222965.
↑ Saumarez RC, Camm AJ, Panagos A, Gill JS, Stewart JT, de Belder MA, Simpson IA, McKenna WJ (August 1992). "Ventricular fibrillation in hypertrophic cardiomyopathy is associated with increased fractionation of paced right ventricular electrograms". Circulation. 86 (2): 467–74. doi:10.1161/01.cir.86.2.467. PMID 1638716.
↑ Bektas, Firat; Soyuncu, Secgin (2012). "Hypokalemia-induced Ventricular Fibrillation". The Journal of Emergency Medicine. 42 (2): 184–185. doi:10.1016/j.jemermed.2010.05.079. ISSN 0736-4679.
↑ Klasner, Ann E; Scalzo, Anthony J; Blume, Carolyn; Johnson, Paul; Thompson, Michael W (1996). "Marked Hypocalcemia and Ventricular Fibrillation in Two Pediatric Patients Exposed to a Fluoride-Containing Wheel Cleaner". Annals of Emergency Medicine. 28 (6): 713–718. doi:10.1016/S0196-0644(96)70097-5. ISSN 0196-0644.
↑ Billman GE, Hoskins RS (November 1988). "Cocaine-induced ventricular fibrillation: protection afforded by the calcium antagonist verapamil". FASEB J. 2 (14): 2990–5. doi:10.1096/fasebj.2.14.3181653. PMID 3181653.
↑ ^8.0 ^8.1 Heist, E. Kevin; Ruskin, Jeremy N. (2010). "Drug-Induced Arrhythmia". Circulation. 122 (14): 1426–1435. doi:10.1161/CIRCULATIONAHA.109.894725. ISSN 0009-7322.
↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
↑ Alings, Marco; Wilde, Arthur (1999). ""Brugada" Syndrome". Circulation. 99 (5): 666–673. doi:10.1161/01.CIR.99.5.666. ISSN 0009-7322.
↑ Gurabi Z, Koncz I, Patocskai B, Nesterenko VV, Antzelevitch C (February 2014). "Cellular mechanism underlying hypothermia-induced ventricular tachycardia/ventricular fibrillation in the setting of early repolarization and the protective effect of quinidine, cilostazol, and milrinone". Circ Arrhythm Electrophysiol. 7 (1): 134–42. doi:10.1161/CIRCEP.113.000919. PMC 3951442. PMID 24429494.
↑ Jain PK, Sharma AK, Agarwal N, Jain PK, Sengar NS, Agarwal N; et al. (2013). "A prospective clinical study of myocarditis in cases of acute ingestion of paraphenylene diamine (hair dye) poisoning in northern India". J Assoc Physicians India. 61 (9): 633–6, 644. PMID 24772701.

Template:WH Template:WS

[pmid19252119-1] Koplan BA, Stevenson WG (March 2009). "Ventricular tachycardia and sudden cardiac death". Mayo Clin. Proc. 84 (3): 289–97. doi:10.1016/S0025-6196(11)61149-X. PMC 2664600. PMID 19252119.

[pmid27250216-2] Khairy P (November 2016). "Ventricular arrhythmias and sudden cardiac death in adults with congenital heart disease". Heart. 102 (21): 1703–1709. doi:10.1136/heartjnl-2015-309069. PMID 27250216.

[pmid28222965-3] Maury P, Sacher F, Rollin A, Mondoly P, Duparc A, Zeppenfeld K, Hascoet S (May 2017). "Ventricular arrhythmias and sudden death in tetralogy of Fallot". Arch Cardiovasc Dis. 110 (5): 354–362. doi:10.1016/j.acvd.2016.12.006. PMID 28222965.

[pmid1638716-4] Saumarez RC, Camm AJ, Panagos A, Gill JS, Stewart JT, de Belder MA, Simpson IA, McKenna WJ (August 1992). "Ventricular fibrillation in hypertrophic cardiomyopathy is associated with increased fractionation of paced right ventricular electrograms". Circulation. 86 (2): 467–74. doi:10.1161/01.cir.86.2.467. PMID 1638716.

[BektasSoyuncu2012-5] Bektas, Firat; Soyuncu, Secgin (2012). "Hypokalemia-induced Ventricular Fibrillation". The Journal of Emergency Medicine. 42 (2): 184–185. doi:10.1016/j.jemermed.2010.05.079. ISSN 0736-4679.

[KlasnerScalzo1996-6] Klasner, Ann E; Scalzo, Anthony J; Blume, Carolyn; Johnson, Paul; Thompson, Michael W (1996). "Marked Hypocalcemia and Ventricular Fibrillation in Two Pediatric Patients Exposed to a Fluoride-Containing Wheel Cleaner". Annals of Emergency Medicine. 28 (6): 713–718. doi:10.1016/S0196-0644(96)70097-5. ISSN 0196-0644.

[pmid3181653-7] Billman GE, Hoskins RS (November 1988). "Cocaine-induced ventricular fibrillation: protection afforded by the calcium antagonist verapamil". FASEB J. 2 (14): 2990–5. doi:10.1096/fasebj.2.14.3181653. PMID 3181653.

[HeistRuskin2010-8] 8.0 ^8.1 Heist, E. Kevin; Ruskin, Jeremy N. (2010). "Drug-Induced Arrhythmia". Circulation. 122 (14): 1426–1435. doi:10.1161/CIRCULATIONAHA.109.894725. ISSN 0009-7322.

[9] Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016

[10] Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

[AlingsWilde1999-11] Alings, Marco; Wilde, Arthur (1999). ""Brugada" Syndrome". Circulation. 99 (5): 666–673. doi:10.1161/01.CIR.99.5.666. ISSN 0009-7322.

[pmid24429494-12] Gurabi Z, Koncz I, Patocskai B, Nesterenko VV, Antzelevitch C (February 2014). "Cellular mechanism underlying hypothermia-induced ventricular tachycardia/ventricular fibrillation in the setting of early repolarization and the protective effect of quinidine, cilostazol, and milrinone". Circ Arrhythm Electrophysiol. 7 (1): 134–42. doi:10.1161/CIRCEP.113.000919. PMC 3951442. PMID 24429494.

[pmid24772701-13] Jain PK, Sharma AK, Agarwal N, Jain PK, Sengar NS, Agarwal N; et al. (2013). "A prospective clinical study of myocarditis in cases of acute ingestion of paraphenylene diamine (hair dye) poisoning in northern India". J Assoc Physicians India. 61 (9): 633–6, 644. PMID 24772701.

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