COVID-19 historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Coronavirus, named due to the "crown" like appearance of its surface projections, was first isolated from chickens in 1937.
In 1965, Tyrrell and Bynoe used cultures of human ciliated embryonal trachea to propagate the first human coronavirus (HCoV) in vitro.
There are now approximately 15 species in this family, which infect not only humans but cattle, pigs, rodents, cats, dogs and birds (some are serious veterinary pathogens, especially chickens).^[1]