COVID-19 Neurologic Complications

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D., Rinky Agnes Botleroo, M.B.B.S.

Complications in the Central Nervous System

Cerebrovascular Accident/Stroke

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Acute Encephalitis

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Viral Meningitis

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Epileptic Seizures

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Encephalopathy

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Headache

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Complications in the Peripheral Nervous system

Guillain-Barre syndrome

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Anosmia

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Acute Myelitis

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Miller Fischer Sydrome

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Polyneuritis Cranialis

• Pathophysiology
• Natural history
• Sign and symptoms
• Diagnosis
• Treatment

Complications due to medication interaction

1. Statin induced myotoxicity

• Myalgia, myopathies, rhabdomyolysis

2. 2nd and 3rd degree atrioventricular block

• Lopinavir/ Ritonavir (Kaltera) (400 mg/100 mg)

3. Prolong QTc interval

• Chloroquine/Hydroxychloroquine

4. Myelotoxicity

• Ribavirin

5. Prolonged PR interval

• Atazanavir

6. Myelosuppression

7.