COVID-19 classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), can be categorized into two major types, L, the major type (~70%) and S, the minor type (~30%).
Classification
- SARS-CoV-2 viruses, the etiological agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types:[1]
- L, the major type (~70%)
- S, the minor type (~30%)
Establishing the Classification
- One hundred and three SARS-CoV-2 virus strains were studied.[1]
- One hundred and one of them exhibited complete linkage between the two single nucleotide polymorphisms (SNPs): 72 strains exhibited a “CT” haplotype (defined as L type because T28,144 is in the codon of Leucine) and 29 strains exhibited a “TC” haplotype (defined as S type because C28,144 is in the codon of Serine) at these two sites.