Covid-19 Associated Respiratory Failure

	Infra-Hisian Block Microchapters
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Treatment
Prevention
Differentiating Infra-Hisian Block from other Diseases

Overview

On 31 December 2019, the World Health Organization (WHO) was formally notified about a cluster of cases of pneumonia in Wuhan City.^[1]
Ten days later, WHO was aware of 282 confirmed cases, of which four were in Japan, South Korea and Thailand
The virus responsible was isolated on 7 January and its genome shared on 12 January.The cause of the severe acute respiratory syndrome that became known as COVID‐19 was a novel coronavirus, SARS‐CoV‐2
ARDS is one of the most important causes of hospital and ICU admission due to COVID.
Many autopsies studies reported ARDS to be the cause of death in patients dying due to respiratory complications of COVID.

As of July 19 2020 the number of total cases worldwide are 14,043,176 including 597,583 deaths, reported to WHO.

**Classification of Waldenstrom macroglobulinemia (WM) and Related Disorders**
Criteria	Symptomatic WM	Asymptomatic WM	IgM-Related Disorders	MGUS
IgM monoclonal protein	+	+	+	+
Bone marrow infiltration	+	+	-	-
Symptoms attributable to IgM	+	-	+	-
Symptoms attributable to tumor infiltration	+	-	-	-

↑ ^1.0 ^1.1 Chaplin, Steve (2020). "COVID ‐19: a brief history and treatments in development". Prescriber. 31 (5): 23–28. doi:10.1002/psb.1843. ISSN 0959-6682. line feed character in |title= at position 6 (help)
↑ Kiran U, Aggarwal S, Choudhary A, Uma B, Kapoor PM (2017). "The blalock and taussig shunt revisited". Ann Card Anaesth. 20 (3): 323–330. doi:10.4103/aca.ACA_80_17. PMC 5535574. PMID 28701598.