Renal agenesis natural history, complications and prognosis
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Overview
Complications of unilateral renal agenesis (URA) may include signs of renal injury such as: hypertension, microalbuminuria and chronic kidney disease. Prognosis of bilateral renal agenesis (BRA) is extremely poor, and the mortality rate is 100% without prenatal therapy with serial amnioinfusion.
Natural History, Complications, and Prognosis
Natural History
Complications
Complications of unilateral renal agenesis (URA) may include signs of renal injury such as: (westland)
- Hypertension (16%)
- Microalbuminuria (21%)
- GFR <60 mL/min/1.73 m² (chronic kidney disease) (10%)
Prognosis
- Prognosis of bilateral renal agenesis (BRA) is extremely poor, and the mortality rate is 100% without prenatal therapy with serial amnioinfusion. (huber)