Renal agenesis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Renal agenesis results from the failure of the ureteric bud to form the ureter, renal pelvis and the collecting duct system and the failure of the renal mesenchyme to form nephrons.
Pathophysiology
- Renal development (interactions between the ureteric bud (mesonephric duct) and the metanephric mesenchyme) starts at the 5th week of gestation. (3in westland
- Renal agenesis results from: (4 in westland)
- Failure of the ureteric bud to form the ureter, renal pelvis and the collecting duct system
- Failure of the renal mesenchyme to form nephrons
- Renal agenesis is a congenital condition caused by complete failure of embryonic kidney formation. (laurich)
- Unilateral renal agenesis (URA) is the one-sided congenital failure of embryonic kidney formation [1, 2 in westland].