Sandbox:Sahar

Drug Class	Drug	Initial daily dose, target dose (mg)	Preferred use	Preferably combined with
Thiazide diuretics	Chlorthalidone	12.5, 12.5-25	Heart failure, isolated systolic hypertension, black population	ACE inhibitors, ARBs, calcium channel blockers
	Hydrochlorothiazide	12.5-25, 25-100
	Bendroflumethiazide	5, 10
	Indapamide	1.25, 1.25-2.5
ACE inhibitors	Enalapril	5, 20	Left ventricular hypertrophy, atherosclerosis, renal insufficiency, previous myocardial infarction, heart failure, atrial fibrillation (prevention), peripheral artery disease, metabolic syndrome, diabetes mellitus	Calcium channel blockers, thiazide diuretics
	Lisinopril	10, 40
	Captopril	50, 150-200
ARBs	Candesartan	4, 12-32	Left ventricular hypertrophy, renal insufficiency, previous myocardial infarction, heart failure, atrial fibrillation (prevention), metabolic syndrome, diabetes mellitus	Calcium channel blockers, thiazide diuretics
	Losartan	50, 100
	Valsartan	40-80, 160-320
	Eprosartan	400, 600-800
	Irbesartan	75, 300
Beta blockers	Atenolol	25-50, 100	Previous myocardial infarction, atrial fibrillation (prevention and ventricular rate control), heart failure, angina pectoris, aortic aneurysm, pregnancy	Thiazide diuretics (with limitations) Only dihydropyridine calcium channel blockers should be combined with beta blockers
	Metoprolol succinate	50, 100-200
Calcium channel blockers	Amlodipine	2.5, 10	Left ventricular hypertrophy, pregnancy (nifedipine), previous myocardial infarction, atrial fibrillation (verapamil, diltiazem), metabolic syndrome, peripheral artery disease, atherosclerosis, angina pectoris, isolated systolic hypertension, black population	ACE inhibitors, ARBs, thiazide diuretics
	Diltiazem extended release	120-180, 360
	Nitrendipine	10, 20