Cyanosis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Overview
Natural History, Complications, and Prognosis
Natural History
- The symptoms of neonatal cyanosis usually develop in the first hours or days of life.[1]
- Acrocyanosis or peripheral cyanosis is a physiologic finding limited to extremities and causes by slowing flow through the peripheral capillary bed and large difference between arteriovenous oxygen content.
- The symptoms of central cyanosis is present as bluish of mucous membranes and tongue.
- Early clinical features related to central cyanosis include severe respiratory distress, tachycardia, tachypnea, apnea and need to immediate evaluation.
- Central cyanosis implies life threatening condition in neonate such as congenital cardiac abnormalities , airway obstruction , central nerve system problem, hemoglobinopathy.
Complications
- Common complications of underlying causes of Central cyanosis in neonate include airway obstruction, hyporventilation due to CNS disease or apnea and circulatory collapse.
Prognosis
- Prognosis is generally good and dependent on the diagnosis and treatment of underlying causes.
- The 10-year survival rate of children with severe congenital heart disease is approximately 90%.
References
- ↑ Sasidharan P (August 2004). "An approach to diagnosis and management of cyanosis and tachypnea in term infants". Pediatr Clin North Am. 51 (4): 999–1021, ix. doi:10.1016/j.pcl.2004.03.010. PMID 15275985.