Sandbox:Lina Alatta
Gastroenterology
Celiac Disease
Overview
Celiac disease is an immune-mediated sensitivity to gluten in genetically suspected individuals that mainly affects the small intestinal mucosa. [1]
Historical Perspectives
Celiac disease was first discovered by Dutch pediatricians in late 1940, as a disease caused by gluten. After that, main changes was done in realizing the disease pathogenesis, diagnosis and treatment.[2]
==
Patients with celiac disease presents at young age with:
- GIT symptoms
- Dermatological symptoms
- Vitamin def
Physical Examinations
References
- ↑ Freeman HJ (2015). "Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms". Gut Liver. 9 (1): 28–37. doi:10.5009/gnl14288. PMC 4282854. PMID 25547088.
- ↑ Murray JA, Frey MR, Oliva-Hemker M (2018). "Celiac Disease". Gastroenterology. 154 (8): 2005–2008. doi:10.1053/j.gastro.2017.12.026. PMC 6203336. PMID 29550590.