Anaphylaxis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD
Epidemiology and Demographics
Prevalence
- In 2006, the lifetime prevalence of Anaphylaxis was estimated to be 0.05% to 2% in the United States. However it is believed that this is an underestimation because the disease is underdiagnosed. [1]
Case-fatality rate/Mortality rate
- The mortality rate of Anaphylaxis is approximately 186 to 225 deaths/year. [2]
Age
- Patients of all age groups may develop anaphylaxis, however, children and adolescents account for the majority of cases.[3]
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
An estimated 1.24% to 16.8% of the population of the United States is considered "at risk" for having an anaphylactic reaction if they are exposed to one or more allergens, especially penicillin and insect stings. Most of these people successfully avoid their allergens and will never experience anaphylaxis. Of those people who actually experience anaphylaxis, up to 1% may die as a result.[4] Anaphylaxis results in fewer than 1,000 deaths per year in the U.S. (compared to 2.4 million deaths from all causes each year in the U.S.[5]). The most common presentation includes sudden cardiovascular collapse (88% of reported cases of severe anaphylaxis).
Developing Countries
References
- ↑ LoVerde D, Iweala OI, Eginli A, Krishnaswamy G (2018). "Anaphylaxis". Chest. 153 (2): 528–543. doi:10.1016/j.chest.2017.07.033. PMC 6026262. PMID 28800865.
- ↑ Ma L, Danoff TM, Borish L (2014). "Case fatality and population mortality associated with anaphylaxis in the United States". J Allergy Clin Immunol. 133 (4): 1075–83. doi:10.1016/j.jaci.2013.10.029. PMC 3972293. PMID 24332862.
- ↑ Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A; et al. (2006). "Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group". Ann Allergy Asthma Immunol. 97 (5): 596–602. doi:10.1016/S1081-1206(10)61086-1. PMID 17165265.
- ↑ Neugut, Alfred, Anita Ghatak and Rachel Miller. "Anaphylaxis in the United States: An Investigation Into Its Epidemiology." Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.
- ↑ "FASTSTATS - Deaths and Mortality". Retrieved 2013-02-13.