Delirium future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]

Overview

There are many still unknown about delirium. Studies are being conducted to understand pathophysiology, more effective ways of prevention, utilization of EEG and CT/MRI scan etc.

Future or Investigational Therapies

Currently many studies are being conducted such as;

Prevention of Delirium

Melatonin^[1]

Ramelteon^[2]

Dexmedetomidine^[3]

Studies to Improve Diagnosis and Prevention of Delirium

Transcranial doppler to diagnose and monitor delirium
MRI
EEG

Studies to Understand Pathophysiology of Delirium

Role of the immune system
Peri-operative delirium

References

↑ Grover, Sandeep; Dua, Devakshi; Sahoo, Swapnajeet; Chakrabarti, Subho; Avasthi, Ajit (2019). "Effectiveness of melatonin in the management of delirium: A retrospective study". Journal of Mental Health and Human Behaviour. 24 (2): 78. doi:10.4103/jmhhb.jmhhb_56_19. ISSN 0971-8990.
↑ . doi:10.1097/CCM.0000000000003132. Check |doi= value (help). Missing or empty |title= (help)
↑ Ng, K. T.; Shubash, C. J.; Chong, J. S. (2019). "The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis". Anaesthesia. 74 (3): 380–392. doi:10.1111/anae.14472. ISSN 0003-2409.

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[GroverDua2019-1] Grover, Sandeep; Dua, Devakshi; Sahoo, Swapnajeet; Chakrabarti, Subho; Avasthi, Ajit (2019). "Effectiveness of melatonin in the management of delirium: A retrospective study". Journal of Mental Health and Human Behaviour. 24 (2): 78. doi:10.4103/jmhhb.jmhhb_56_19. ISSN 0971-8990.

[2] . doi:10.1097/CCM.0000000000003132. Check |doi= value (help). Missing or empty |title= (help)

[NgShubash2019-3] Ng, K. T.; Shubash, C. J.; Chong, J. S. (2019). "The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis". Anaesthesia. 74 (3): 380–392. doi:10.1111/anae.14472. ISSN 0003-2409.

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