Pyonephrosis pathophysiology
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Pyonephrosis can be seen as a complication of Acute Pyelonephritis, usually seen with complete or incomplete obstruction of tubules[1]. Obstruction of ureter and renal pelvis leads to dilatation of tubular system and leads to Hydronephrosis. This dilatation becomes a nidus for infection. The pathogen multiply easily in obstructed and dilated tubules leading to suppurative inflammation. The exudates fill the tubules, renal pelvis, calyces and ureter with pus that is difficult to drain.
References
- ↑ Kumar, Vinay (2015). Robbins and Cotran pathologic basis of disease. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-2613-4.