Rift valley fever causes
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Rift valley fever Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aakash Hans, MD[2]
Overview
Causes
- RVF is caused by the Rift Valley fever virus or RVFV, which belongs to the Bunyaviridae family.
- The genetic composition of the virus is a single-stranded RNA consisting of three segments (L, M and S) out of which L and M possess a negative charge while the S segment has both sense and antisense orientation.[1]
- The virus’ RNA polymerase is coded by the L component which is responsible for replication and transcription of messenger RNA (mRNA) while glycoproteins and protein are encoded via the M segment. [2]
- Nucleoproteins and non-structural proteins are coded by the S segment in its antisense and sense orientation respectively.
Gallery
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![High magnification transmission electron micrograph (TEM) reveals some of the ultrastructural morphology seen in an unknown tissue sample, which had been caused by the spherical-shaped, enveloped Rift Valley fever (RVF) virus. Virions budding from the cell membrane are indicated by arrowheads. From Public Health Image Library (PHIL). [3]](/images/d/d5/Phlebovirus06.jpeg)
High magnification transmission electron micrograph (TEM) reveals some of the ultrastructural morphology seen in an unknown tissue sample, which had been caused by the spherical-shaped, enveloped Rift Valley fever (RVF) virus. Virions budding from the cell membrane are indicated by arrowheads. From Public Health Image Library (PHIL). [3]
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![Transmission electron micrograph (TEM) depicts a highly magnified view of a tissue that had been infected with Rift Valley fever (RVF) virus. From Public Health Image Library (PHIL). [3]](/images/3/31/Phlebovirus04.jpeg)
Transmission electron micrograph (TEM) depicts a highly magnified view of a tissue that had been infected with Rift Valley fever (RVF) virus. From Public Health Image Library (PHIL). [3]
![High magnification transmission electron micrograph (TEM) reveals some of the ultrastructural morphology seen in an unknown tissue sample, which had been caused by the spherical-shaped, enveloped Rift Valley fever (RVF) virus. Virions budding from the cell membrane are indicated by arrowheads. From Public Health Image Library (PHIL). [3]](/index.php/File:Phlebovirus06.jpeg)
![Transmission electron micrograph (TEM) depicts a highly magnified view of a tissue that had been infected with Rift Valley fever (RVF) virus. From Public Health Image Library (PHIL). [3]](/index.php/File:Phlebovirus04.jpeg)
References
- ↑ Giorgi C. et al. 1991. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology 180:738–753
- ↑ Gerrard S. R. and Nichol S. T.. 2007. Synthesis, proteolytic processing and complex formation of N-terminally nested precursor proteins of the Rift Valley fever virus glycoproteins. Virology 357:124–133.
- ↑ 3.0 3.1 "Public Health Image Library (PHIL)".