Alcoholic hepatitis historical perspective

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Overview

Alcoholic hepatitis was first recognized in 1961 after investigation of 7 cases with excessive alcohol intake . Before the recognition of Alcoholic Hepatitis, it was believed that the symptoms are caused by malnutrition not due to toxic effects of alcohol. Charles S. Lieber developed modern research on alcohol-related liver disease.

Charles S. Lieber was the first one who developed modern research on alcohol and alcohol-related liver damage.^[1]
In 1950s, it was believed that alcohol-related liver damage is related to malnutrition rather than toxic effects of alcohol.^[1]
In 1961, Beckett and his colleagues used the term Alcoholic Hepatitis for the first time.^[2]
Beckett et al. investigated 7 cases of acute Alcoholic Hepatitis and their features at Royal Free Hospital in Great Britain during 1953-1961.^[2]

↑ ^1.0 ^1.1 Neuman, M. G.; Cohen, L.; Zakhari, S.; Nanau, R. M.; Mueller, S.; Schneider, M.; Parry, C.; Isip, R.; Seitz, H. K. (2014). "Alcoholic Liver Disease: A Synopsis of the Charles Lieber's Memorial Symposia 2009-2012". Alcohol and Alcoholism. 49 (4): 373–380. doi:10.1093/alcalc/agu021. ISSN 0735-0414.
↑ ^2.0 ^2.1 Beckett, A. G.; Livingstone, A. V.; Hill, K. R. (1961). "Acute Alcoholic Hepatitis". BMJ. 2 (5260): 1113–1119. doi:10.1136/bmj.2.5260.1113. ISSN 0959-8138.