Alcoholic hepatitis primary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Primary Prevention
- The primary prevention of Alcoholic Hepatitis is alcohol abstinence[1]
- Alcohol abstinence improves histological features of hepatic injury and reduces portal hypertension and the risk of cirrhosis[2]
- In two-third of patients improvement can be seen in 90 days[3]
- Risk of recidivism is 67% to 81% after alcohol abstinence [4]
- In order to decrease the risk of recidivism, following interventions are recommended:[5]
- Combination psychotherapy with cognitive behavioral therapy
- Peer driven support counseling
- Motivational enhancement therapy
- Comprehensive medical care
References
- ↑ Pessione F, Ramond MJ, Peters L, Pham BN, Batel P, Rueff B; et al. (2003). "Five-year survival predictive factors in patients with excessive alcohol intake and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence". Liver Int. 23 (1): 45–53. doi:10.1034/j.1600-0676.2003.01804.x. PMID 12640727.
- ↑ O'Shea RS, Dasarathy S, McCullough AJ (2010). "Alcoholic liver disease". Am J Gastroenterol. 105 (1): 14–32, quiz 33. doi:10.1038/ajg.2009.593. PMID 19904248.
- ↑ Veldt BJ, Lainé F, Guillygomarc'h A, Lauvin L, Boudjema K, Messner M; et al. (2002). "Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing". J Hepatol. 36 (1): 93–8. doi:10.1016/s0168-8278(01)00228-8. PMID 11804670.
- ↑ Miller WR, Walters ST, Bennett ME (2001). "How effective is alcoholism treatment in the United States?". J Stud Alcohol. 62 (2): 211–20. doi:10.15288/jsa.2001.62.211. PMID 11327187.
- ↑ Khan A, Tansel A, White DL, Kayani WT, Bano S, Lindsay J; et al. (2016). "Efficacy of Psychosocial Interventions in Inducing and Maintaining Alcohol Abstinence in Patients With Chronic Liver Disease: A Systematic Review". Clin Gastroenterol Hepatol. 14 (2): 191-202.e1-4, quiz e20. doi:10.1016/j.cgh.2015.07.047. PMC 4805368. PMID 26256464.