Peripartum mood disturbances natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunita Kumawat, M.B.B.S[2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

• Postpartum blues are characterized by mild, temporary, and self-limiting mood disturbances.
• Postpartum blues puts a woman at risk of postpartum depression, postpartum psychosis and postpartum anxiety disorders.
  

• If left untreated, females with postpartum depression may progress to develop chronic depressive disorder, and are predisposed to major depression in future. This can also result in depression in father.
• Children of untreated females may have emotional, behavioural issues and language problems. Greater chances of having ADHD, excessive crying, eating and sleeping problems. This condition can impact bonding between mother and child.
  

• Postpartum psychosis is a psychiatric emergency and patient needs immediate treatment. Majority of individuals with postpartum psychosis react well to therapy and have rapid recovery and remission. Suffering from postpartum psychosis increases its likelihood in future pregnancy.
• Common complications of postpartum psychosis, if left untreated include filicide, suicide, and many psychosocial implications.

Natural History

• The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
• The symptoms of (disease name) typically develop ___ years after exposure to ___.
• If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

• Common complications of [disease name] include:
  • [Complication 1]
  • [Complication 2]
  • [Complication 3]

Prognosis

• Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
• Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
• The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
• [Subtype of disease/malignancy] is associated with the most favorable prognosis.
• The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.