Hyperemesis gravidarum pathophysiology

Hyperemesis gravidarum Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Development of hyperemesis gravidarum is the result from multiple genetic mutations. Hyperemesis gravidarum usually develops during the 2nd trimester of pregnancy.

Genetics

Hyperemesis gravidarum is transmitted in dominant pattern. Gene 1B-alpha2Y is highly associated with hyperemesis gravidarum and twin pregnancies.

Associated Conditions

The most important conditions associated with hyperemesis gravidarum include:

• Molar pregnancy
• Twins
• Down syndrome