Pyonephrosis (patient information)
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Polynephrosis |
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Polynephrosis On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Harsh Vardhan Chawla, M.B.B.S.[2]
Overview
Pyonephrosis (Greek pyon "pus" + nephros "kidney") is an infection of obstructed renal collecting system leading to accumulation of pus in the renal collecting system. Pus collects in the renal pelvis and eventually causes destruction of the renal parenchyma. Pyonephrosis is sometimes a complication of renal stones, which can be a source of persisting infection. It may also occur spontaneously.
It needs an early diagnosis and immediate intervention as it may progress to urosepsis. Treatment may require drainage, best performed by nephrostomy.
What are the symptoms of pyonephrosis?
Patients with pyonephrosis present with the following symptoms:
- Fever
- Chills
- Flank pain, back pain, abdominal pain
- Nausea and vomiting
- Fatigue
- Frequent urination
- Burning sensation when urinating
- Foul smelling urine
- Blood or pus in urine
What causes pyonephrosis?
- Pyonephrosis is commonly caused by bacteria like Escherichia coli, Enterococcus species among others.
- Accumulation of pus as a result of an ongoing upper urinary tract infection (acute pyelonephritis) combined with inability to drain due to obstruction of the renal collecting system results in pyonephrosis.
Who is at highest risk?
Factors that increase the risk of pyonephrosis are:
- Obstruction of the urinary tract: This includes conditions that reduces the flow of urine and the ability to empty the bladder (urinary retention) such as enlarged prostate in elderly men, kidney stones, ureteral strictures, tumors.
- Immunocompromised conditions: This includes medical conditions that weaken the body's defence mechanisms, such as diabetes mellitus and AIDS. Certain medications, such as steroids, anti-cancer drugs also compromise the immunity.
- Damaged nerves supplying the bladder: Lack of bladder control due to brain, spinal cord or nerve problems which can lead to urinary retention or leakage.
- Pregnancy: The hormonal and mechanical changes in the urinary tract promotes stasis of urine and a tendency of the urine to go back up the ureters. Coupled with difficulty in maintaining hygiene due to distended abdomen and already shorter urethra in females, increases the risk of pyonephrosis.
Diagnosis
When to seek urgent medical care?
Treatment options
Where to find medical care for pyonephrosis?
Directions to Hospitals Treating Condition
Prevention
What to expect (Outlook/Prognosis)?
Possible complications
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