Monkeypox history and symptoms
Interim clinical, laboratory and epidemiologic criteria for case classification — U.S. Monkeypox Response, May 2022
| Clinical and laboratory classification | Criteria |
| Suspected | New characteristic rash* OR |
| Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | |
| Probable | No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) AND demonstration of the presence of |
| • Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen OR | |
| • Orthopoxvirus using immunohistochemical or electron microscopy testing methods
start highlight OR end highlight | |
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• Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset end highlight | |
| Confirmed | Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen OR |
| Isolation of Monkeypox virus in culture from a clinical specimen | |
| Epidemiologic classification |
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Monkeypox Microchapters |
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Diagnosis |
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Treatment |
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Monkeypox history and symptoms On the Web |
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American Roentgen Ray Society Images of Monkeypox history and symptoms |
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Risk calculators and risk factors for Monkeypox history and symptoms |