Monkeypox history and symptoms
Interim clinical, laboratory and epidemiologic criteria for case classification — U.S. Monkeypox Response, May 2022
Clinical and laboratory classification | Criteria |
Suspected | New characteristic rash* OR |
Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | |
Probable | No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) AND demonstration of the presence of |
• Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen OR | |
• Orthopoxvirus using immunohistochemical or electron microscopy testing methods
OR | |
• Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset | |
Confirmed | Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen
OR |
Isolation of Monkeypox virus in culture from a clinical specimen |
Monkeypox Microchapters |
Diagnosis |
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Treatment |
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