Biliary atresia other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Other Imaging Findings

Nuclear medicine (hepatobiliary (HIDA) scan)

Cases of biliary atresia typically demonstrate relatively good hepatic uptake with no evidence of excretion into the bowel at 24 hours. Pretreatment with phenobarbital (5 mg/kg/day for 5 days) is done to stimulate hepatic enzymes in order to increase biliary secretion. This is helpful to minimize the possibility of a false-positive study due to pre-existing poor excretion. Radiotracers used are Tc-99m diosgenin (DISIDA) and mebrofenin (BRIDA) due to high hepatic extraction and short transit time.

Further testing include radioactive scans of the liver and a liver biopsy.