Anti-NMDA receptor encephalitis historical perspective

Anti-NMDA receptor encephalitis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Anti-NMDA receptor encephalitis from Other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications, and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Anti-NMDA receptor encephalitis historical perspective On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Anti-NMDA receptor encephalitis historical perspective All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Anti-NMDA receptor encephalitis historical perspective
CDC on Anti-NMDA receptor encephalitis historical perspective
Anti-NMDA receptor encephalitis historical perspective in the news
Blogs on Anti-NMDA receptor encephalitis historical perspective
Directions to Hospitals Treating Anti-NMDA receptor encephalitis
Risk calculators and risk factors for Anti-NMDA receptor encephalitis historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Historical Perspective

In the year 1830, a case report published in top medical journals in Hungarian, German, and Italian medical journals which can be traced back to as anti NMDA encephalitis associated with ovarian teratoma.

• A healthy 18-year-old woman experienced epileptic seizures, followed by six days of catalepsy, unresponsiveness, immobility, and shallow breathing. Her symptoms resurfaced frequently over the next 1.5 years. An ovarian tumor was diagnosed and removed leading to resolution of symptoms.

• In 2007 by Dalmau and Bataller, documented Anti-NMDA receptor encephalitis for the first time and demonstrated antibodies to a subunit of the NMDA glutamate receptor in patients with the condition neuropsychiatric manifestations.

The Susannah Cahalan case is a famous case of Anti NMDA Encephalitis and with publication of Brain on Fire—My Month of Madness in 2012 by New York Post reporter Susannah Cahalan, public awareness of this disorder rose. She described a quick progression from prodromal upper respiratory symptoms like a virus to acute psychosis which was confirmed with biopsy of her brain. She later recovered and continued her job.