Anti-NMDA receptor encephalitis causes

Anti-NMDA receptor encephalitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; AE Dheeraj Makkar, M.D.[2]

Causes

Antibodies and the tumors producing them

Antibodies	Antigens	Associated symptoms	Tumors
Anti-Hu (ANNA-1)	HuD	Encephalomyelitis, limbic encephalitis, cerebellar degeneration, brain stem encephalitis, multi-segmental myelitis, sensory neuronopathy, sensory motor neuropathy, autonomic neuropathy	Lung cancer (85%), mostly SCLC, neuroblastoma, prostate carcinoma
Anti-Yo (PCA-1)	CDR2, CDR62	Paraneoplastic cerebellar degeneration	Ovarian, breast cancer
Anti-CV2(CRMP5)	CRMP5	Encephalomyelitis, polyneuropathy, optic neuritis, limbic encephalitis, choreatic syndromes, cerebellar degeneration	SCLC, thymoma
Anti-Ta/Ma2	MA-proteins	Limbic encephalitis, rhombencephalitis, male>>female	Testicular cancer
Anti-Ri (ANNA-2)	NOVA-1	Opsoclonus–myoclonus syndrome, rhombencephalitis, cerebellar degeneration, myelitis, jaw dystonia, laryngospasm	Breast, ovarian carcinoma, SCLC
Anti-amphiphysin	Amphiphysin	Stiff-person syndrome, limbic encephalitis, rhombencephalitis, cerebellar degeneration, polyneuropathy	Breast cancer, SCLC