Limbic encephalitis
| Limbic encephalitis | |
 | |
|---|---|
| The limbic system within the brain. | |
| ICD-10 | G13.1 |
| DiseasesDB | 30707 |
| MeSH | D020363 |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Limbic encephalitis is a form of encephalitis.
In a small number of cases, the pathogens responsible for encephalitis attack primarily the limbic system (a collection of structures at the base of the brain responsible for basic autonomic functions), often causing memory deficits similar to those observed in Alzheimer's disease or Creutzfeldt-Jakob disease (although limbic encephalitis does not cause the same cognitive deficits as these diseases.[1] Unfortunately for 20% of people with the diagnosis of limbic encephalitis an MRI will not show any neurological abnormalities [2]
60% of the time, limbic encephalitis is paraneoplastic in origin. [3]
Paraneoplastic limbic encephalitis (PLE) is a particularly severe form of limbic encephalitis caused by neoplasms most commonly associated with small cell lung carcinoma. Whereas the majority of encephalitides are viral in nature, PLE is often associated with cancer. In fact, it is thought that up to 1 in 100 people with cancer have in fact got paraneoplastic limbic encephalitis which is commonly misdiagnosed as neurological diseases such as Alzheimer's.[4]
References
External links