Valaciclovir overdose

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overdose

Caution should be exercised to prevent inadvertent overdose. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored

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Adapted from the FDA Package Insert.