Anophthalmia

Anophthalmia
ICD-10	Q11.0-Q11.1
DiseasesDB	29617
eMedicine	oph/572

WikiDoc Resources for Anophthalmia
Articles
Most recent articles on Anophthalmia Most cited articles on Anophthalmia Review articles on Anophthalmia Articles on Anophthalmia in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Anophthalmia Images of Anophthalmia Photos of Anophthalmia Podcasts & MP3s on Anophthalmia Videos on Anophthalmia
Evidence Based Medicine
Cochrane Collaboration on Anophthalmia Bandolier on Anophthalmia TRIP on Anophthalmia
Clinical Trials
Ongoing Trials on Anophthalmia at Clinical Trials.gov Trial results on Anophthalmia Clinical Trials on Anophthalmia at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Anophthalmia NICE Guidance on Anophthalmia NHS PRODIGY Guidance FDA on Anophthalmia CDC on Anophthalmia
Books
Books on Anophthalmia
News
Anophthalmia in the news Be alerted to news on Anophthalmia News trends on Anophthalmia
Commentary
Blogs on Anophthalmia
Definitions
Definitions of Anophthalmia
Patient Resources / Community
Patient resources on Anophthalmia Discussion groups on Anophthalmia Patient Handouts on Anophthalmia Directions to Hospitals Treating Anophthalmia Risk calculators and risk factors for Anophthalmia
Healthcare Provider Resources
Symptoms of Anophthalmia Causes & Risk Factors for Anophthalmia Diagnostic studies for Anophthalmia Treatment of Anophthalmia
Continuing Medical Education (CME)
CME Programs on Anophthalmia
International
Anophthalmia en Espanol Anophthalmia en Francais
Business
Anophthalmia in the Marketplace Patents on Anophthalmia
Experimental / Informatics
List of terms related to Anophthalmia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Synonyms and Related Keywords: Anophthalmos and microphthalmos, small eye syndrome

Overview

Anophthalmia, also known as anophthalmos (Greek: ανόφθαλμος, "without eye"), is the congenital absence of one or both eyes.

Prevalence

True or primary anophthalmos is very rare. Only when there is complete absence of the ocular tissue within the orbit can the diagnosis of true anophthalmos be made. Extreme microphthalmos is seen more commonly. In this condition, a very small globe is present within the orbital soft tissue, which is not visible on initial examination.

There are three classifications for this condition.

• Primary anophthalmia is a complete absence of eye tissue due to a failure of the part of the brain that forms the eye.
• Secondary anophthalmia the eye starts to develop and for some reason stops, leaving the infant with only residual eye tissue or extremely tiny eyes which can only be seen under close examination.
• Degenerative anophthalmia the eye started to form and, for some reason, degenerated. One reason for this occurring could be a lack of blood supply to the eye.

Causes

Anophthalmia and microphthalmia may occur secondary to the arrest of development of the eye at various stages of growth of the optic vesicle. It is important to recognize microphthalmia because the development of the orbital region, as well as the lids and fornices, is dependent on the presence of a normal-sized eye in utero.

Treatments

Early treatment with various expanders or surgery, when necessary, will help decrease the orbital asymmetry and cosmetic deformities in these children.

External links

• Anophthalmia and Microphthalmia Resource Guide from the National Eye Institute (NEI).
• anophthalmia-ov at NIH/UW GeneTests

Template:SIB
de:Anophthalmie it:Anoftalmia