FEV1/FVC ratio

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The FEV1/FVC ratio is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease.

It represents the proportion of the forced vital capacity exhaled in the first second[1].

Disease States

In obstructive lung disease, the FEV1 is reduced due to obstruction to air escape. Thus, the FEV1/FVC ratio will be reduced[2].

In restrictive lung disease, the FEV1 and FVC are equally reduced due to fibrosis or other lung pathology (not obstructive pathology). Thus, the FEV1/FVC ratio should be approximately normal[3].


References

  1. ↑ http://www.gp-training.net/protocol/respiratory/copd/spirometry.htm
  2. ↑ http://www.gp-training.net/protocol/respiratory/copd/spirometry.htm
  3. ↑ http://www.gp-training.net/protocol/respiratory/copd/spirometry.htm


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