Cefalotin

Cefalotin

Clinical data
Pregnancy category	AU: A
Routes of administration	IV
ATC code	J01DB03 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability	n/a
Protein binding	65 to 80%
Metabolism	Hepatic
Elimination half-life	30 minutes to 1 hour
Excretion	Renal
Identifiers
IUPAC name (6R,7R)-3-(acetoxymethyl)- 8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia- 1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	153-61-7
PubChem CID	6024
DrugBank	APRD00859
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C16H16N2O6S2
Molar mass	396.44 g/mol

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Overview

Cefalotin (INN) (Template:PronEng) or cephalothin (USAN) (Template:IPA) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed and continues to be widely used. It is an intravenously-administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly).

See also

• Cephalosporin
• Cefalexin