Nephrotoxic drugs

	WikiDoc Resources for Nephrotoxic drugs
Articles
Most recent articles on Nephrotoxic drugs Most cited articles on Nephrotoxic drugs Review articles on Nephrotoxic drugs Articles on Nephrotoxic drugs in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Nephrotoxic drugs Images of Nephrotoxic drugs Photos of Nephrotoxic drugs Podcasts & MP3s on Nephrotoxic drugs Videos on Nephrotoxic drugs
Evidence Based Medicine
Cochrane Collaboration on Nephrotoxic drugs Bandolier on Nephrotoxic drugs TRIP on Nephrotoxic drugs
Clinical Trials
Ongoing Trials on Nephrotoxic drugs at Clinical Trials.gov Trial results on Nephrotoxic drugs Clinical Trials on Nephrotoxic drugs at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Nephrotoxic drugs NICE Guidance on Nephrotoxic drugs NHS PRODIGY Guidance FDA on Nephrotoxic drugs CDC on Nephrotoxic drugs
Books
Books on Nephrotoxic drugs
News
Nephrotoxic drugs in the news Be alerted to news on Nephrotoxic drugs News trends on Nephrotoxic drugs
Commentary
Blogs on Nephrotoxic drugs
Definitions
Definitions of Nephrotoxic drugs
Patient Resources / Community
Patient resources on Nephrotoxic drugs Discussion groups on Nephrotoxic drugs Patient Handouts on Nephrotoxic drugs Directions to Hospitals Treating Nephrotoxic drugs Risk calculators and risk factors for Nephrotoxic drugs
Healthcare Provider Resources
Symptoms of Nephrotoxic drugs Causes & Risk Factors for Nephrotoxic drugs Diagnostic studies for Nephrotoxic drugs Treatment of Nephrotoxic drugs
Continuing Medical Education (CME)
CME Programs on Nephrotoxic drugs
International
Nephrotoxic drugs en Espanol Nephrotoxic drugs en Francais
Business
Nephrotoxic drugs in the Marketplace Patents on Nephrotoxic drugs
Experimental / Informatics
List of terms related to Nephrotoxic drugs

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Antibiotics

Aminoglycosides (10-15% Incidence of Acute Tubular Necrosis)

Occurs in 10-20% patients on 7 day course
Results in non-oligurics; increased Creatinine
A single dose early in septic course is usually safe

Sulfonamides
Amphotericin B (Incidence 80-90%)
Levofloxacin
Ciprofloxacin
Rifampin
Tetracycline
Acyclovir (only nephrotoxic in intravenous form)
Pentamidine

Chemotherapy and Immunosuppressants

Heavy Metals

Mercury Poisoning
Lead Poisoning
Arsenic Poisoning
Bismuth
Lithium related kidney disorders

Polydipsia and Nephrogenic Diabetes Insipidus
Acute Renal Failure
- Dialysis indications: Creatinine >2.5 or Seizures, ALOC, Rhabdomyolysis
Chronic kidney disease with fibrosis

AntiHyperlipidemics

Associated with Acute Renal Failure due to Rhabdomyolysis

Fenofibrate (Tricor)

Increases Serum Creatinine without significant decrease in GFR
Serum Creatinine rise is reversible on stopping Fenofibrate

Chemotherapy

Cisplatin
Ifosphamide

Causes Fanconi's Syndrome

Miscellaneous Drugs

Chronic Stimulant Laxative use

Resulting chronic volume depletion and Hypokalemia causes nephropathy

Radiographic contrast
ACE Inhibitors

Expect an increase of Serum Creatinine in Chronic kidney disease

Low dose Aspirin reduces Renal function in elderly
- Decreased Creatinine Clearance after 2 weeks of use
- Changes persisted for at least 3 weeks off Aspirin