Ototoxicity

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WikiDoc Resources for Ototoxicity
Articles
Most recent articles on Ototoxicity Most cited articles on Ototoxicity Review articles on Ototoxicity Articles on Ototoxicity in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Ototoxicity Images of Ototoxicity Photos of Ototoxicity Podcasts & MP3s on Ototoxicity Videos on Ototoxicity
Evidence Based Medicine
Cochrane Collaboration on Ototoxicity Bandolier on Ototoxicity TRIP on Ototoxicity
Clinical Trials
Ongoing Trials on Ototoxicity at Clinical Trials.gov Trial results on Ototoxicity Clinical Trials on Ototoxicity at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Ototoxicity NICE Guidance on Ototoxicity NHS PRODIGY Guidance FDA on Ototoxicity CDC on Ototoxicity
Books
Books on Ototoxicity
News
Ototoxicity in the news Be alerted to news on Ototoxicity News trends on Ototoxicity
Commentary
Blogs on Ototoxicity
Definitions
Definitions of Ototoxicity
Patient Resources / Community
Patient resources on Ototoxicity Discussion groups on Ototoxicity Patient Handouts on Ototoxicity Directions to Hospitals Treating Ototoxicity Risk calculators and risk factors for Ototoxicity
Healthcare Provider Resources
Symptoms of Ototoxicity Causes & Risk Factors for Ototoxicity Diagnostic studies for Ototoxicity Treatment of Ototoxicity
Continuing Medical Education (CME)
CME Programs on Ototoxicity
International
Ototoxicity en Espanol Ototoxicity en Francais
Business
Ototoxicity in the Marketplace Patents on Ototoxicity
Experimental / Informatics
List of terms related to Ototoxicity

Overview

Ototoxicity is damage of the ear (oto), specifically the cochlea or auditory nerve and sometimes the vestibulum, by a toxin (often medication).

Causes

A number of drugs have been associated with damage to the cochlea. The best known are aminoglycoside antibiotics, aspirin, nicotine and some diuretics such as furosemide.

Erythromycin and some other macrolide antibiotics can induce temporary deafness, which resolves upon withdrawal of the drug.

Other chemicals such as toluene, mercury and carbon monoxide are also known Ototoxic chemicals.

There appears to be a hereditary predisposition to ototoxic reactions.

Symptoms

Symptoms include partial or profound hearing loss, vertigo, and tinnitus.

Treatment

No specific treatment is available, but immediate withdrawal of the drug is warranted.

See also

• Toxicity
• Neurotoxicity
• Nephrotoxicity

External links

• Template:GPNotebook
• Ototoxic Medications